All-Star Game — July 8, 1941
AL Roster
25 players
| Pos | Player | Team | Played |
|---|---|---|---|
| P | Bob Feller HOF | Cleveland Indians | Yes |
| C | Bill Dickey HOF | New York Yankees | Yes |
| 1B | Rudy York | Detroit Tigers | Yes |
| 2B | Bobby Doerr HOF | Boston Red Sox | Yes |
| 3B | Cecil Travis | Washington Senators | Yes |
| SS | Joe Cronin HOF | Boston Red Sox | Yes |
| LF | Ted Williams HOF | Boston Red Sox | Yes |
| CF | Joe DiMaggio HOF | New York Yankees | Yes |
| RF | Jeff Heath | Cleveland Indians | Yes |
| — | Al Benton | Detroit Tigers | — |
| — | Birdie Tebbetts | Detroit Tigers | — |
| — | Charlie Keller | New York Yankees | Yes |
| — | Dom DiMaggio | Boston Red Sox | Yes |
| — | Eddie Smith | Chicago White Sox | Yes |
| — | Frankie Hayes | Philadelphia Athletics | Yes |
| — | Jimmie Foxx HOF | Boston Red Sox | Yes |
| — | Joe Gordon HOF | New York Yankees | Yes |
| — | Ken Keltner | Cleveland Indians | Yes |
| — | Lou Boudreau HOF | Cleveland Indians | Yes |
| — | Luke Appling HOF | Chicago White Sox | — |
| — | Marius Russo | New York Yankees | — |
| — | Red Ruffing HOF | New York Yankees | — |
| — | Roy Cullenbine | St. Louis Browns | Yes |
| — | Sid Hudson | Washington Senators | Yes |
| — | Thornton Lee | Chicago White Sox | Yes |
NL Roster
27 players
East-West Game
The East-West Game was the Negro Leagues' showcase, drawing crowds at Comiskey Park that rivaled the major league game. Explore the Negro Leagues.
East Roster
14 players
| Pos | Player | Team | Played |
|---|---|---|---|
| P | Terris McDuffie | Homestead Grays | Yes |
| C | Roy Campanella HOF | Baltimore Elite Giants | Yes |
| 1B | Buck Leonard HOF | Homestead Grays | Yes |
| 2B | Dick Seay | New York Black Yankees | Yes |
| 3B | Monte Irvin HOF | Newark Eagles | Yes |
| SS | Rabbit Martínez | New York Cubans | Yes |
| LF | Bill Hoskins | Baltimore Elite Giants | Yes |
| CF | Henry Kimbro | New York Black Yankees | Yes |
| RF | Pancho Coimbre | New York Cubans | Yes |
| — | Bill Byrd | Baltimore Elite Giants | Yes |
| — | Dave Barnhill | New York Cubans | Yes |
| — | Henry McHenry | Philadelphia Stars | Yes |
| — | Jimmy Hill | Newark Eagles | Yes |
| — | Lennie Pearson | Newark Eagles | Yes |
West Roster
23 players
| Pos | Player | Team | Played |
|---|---|---|---|
| P | Hilton Smith HOF | Kansas City Monarchs | Yes |
| C | Pepper Bassett | Chicago American Giants | Yes |
| 1B | Jelly Taylor | Memphis Red Sox | Yes |
| 2B | Tommy Sampson | Birmingham Black Barons | Yes |
| 3B | Parnell Woods | Jacksonville Red Caps | Yes |
| SS | Newt Allen | Kansas City Monarchs | Yes |
| LF | Dan Wilson | St. Louis-New Orleans Stars | Yes |
| CF | Neil Robinson | Memphis Red Sox | Yes |
| RF | Ted Strong | Kansas City Monarchs | Yes |
| — | Billy Horne | Chicago American Giants | Yes |
| — | Buddy Armour | St. Louis-New Orleans Stars | Yes |
| — | Dan Bankhead | Birmingham Black Barons | Yes |
| — | Duke Cleveland | Jacksonville Red Caps | Yes |
| — | George Mitchell | St. Louis-New Orleans Stars | Yes |
| — | Jimmie Crutchfield | Chicago American Giants | Yes |
| — | Jimmy Ford | St. Louis-New Orleans Stars | Yes |
| — | Larry Brown | Memphis Red Sox | Yes |
| — | Lyman Bostock | Birmingham Black Barons | Yes |
| — | Preacher Henry | Jacksonville Red Caps | Yes |
| — | Satchel Paige HOF | Kansas City Monarchs | Yes |
| — | Ted Radcliffe | Memphis Red Sox | Yes |
| — | Verdell Mathis | Memphis Red Sox | Yes |
| — | Willie Hudson | Chicago American Giants | Yes |